The paper presents materials related to the results of phenological observations of hybrid relatives obtained as a result of crossing with spontaneous mutants of Lemon Meyer trifoliate. We conducted an experiment using the distant hybridization method, in particular, genetically modified trifoliate spontaneous mutants were used as the father component: Mutant #1 and Mutant #2, which do not contain ponzirin, naringin, acrolein and other substances, or contain very small amounts. Meyer lemon plants were included as mother components, which are placed on the collection plots of the Scientific Research Center of Agrarian Directions of Akaki Tsereteli State University. As a result of crossbreeding with lemon Meyer trifoliate sponathan mutants, numerous interesting hybrid relatives were obtained, which will be further studied using genetic and other hybridological methods. The results of the hybridological work carried out by us are a prerequisite for further selective work to be carried out in a wider scope and to obtain the initial material for further successful selective work.